BDBM30140 CHEMBL380049::beta-sulfone piperidine hydroxamate, 2b

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(C)=O)C(=O)NO

InChI Key InChIKey=NPWNPFHGYNOBOO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30140   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM30140(CHEMBL380049 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50:  341nMT: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM30140(CHEMBL380049 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50:  341nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed